Long-term outcomes described for ALL childhood survivors | Health and fitness

Physician Information Staff

THURSDAY, Jan. 20, 2022 (HealthDay News) — In an article published online Dec. 29 in Cancerlong-term negative and positive outcomes are described for survivors of childhood acute lymphoblastic leukemia (ALL).

Charlotte Sleurs, Ph.D., of Leuven University Hospital in Belgium, and her colleagues examined potential risk factors for decreased quality of life and life challenges in long-term childhood ALL survivors. term enrolled in studies between 1971 and 1998. Self-report questionnaires were obtained from 186 survivors (median time since diagnosis, 20.5 years), including the Short Form Health Survey (SF-12) and Impact of Cancer-Childhood Survivors (IOC-CS).

The researchers observed no association between SF-12 mental component scores and any risk factors. National Cancer Institute relapsed, irradiated, and high-risk patients had lower physical component scores. In females, younger patients (less than 6 years old), and relapsed patients, the IOC-CS life challenges subscale was more negatively affected by cancer. In relapsed patients compared to non-relapsed patients, the personal growth subscale was more positively impacted, while body, health, and socialization were less positively impacted. In older patients (over 6 years old), socialization was more positively impacted.

“Given that younger, female, and relapsed patients might experience more life difficulties for many years after treatment, psychosocial support focused on this issue might be recommended,” the authors write. “On the other hand, relapse, radiation and high-risk categorization could result in more physical challenges, which should be addressed with specialized physiotherapeutic interventions, including support for a healthier lifestyle. .”

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